Two cases of esophageal eosinophilia: eosinophilic esophagitis or gastro-esophageal reflux disease?

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Two Cases of Esophageal Eosinophilia: Eosinophilic Esophagitis or Gastro-Esophageal Reflux Disease?

Eosinophilic esophagitis (EoE) and gastroesophageal reflux disease are among the major causes of isolated esophageal eosinophilia. Isolated esophageal eosinophilia meeting criteria for EoE may respond to proton pump inhibitor (PPI) treatment. This entity is termed proton pumps inhibitor responsive esophageal eosinophilia (PPI-REE). Gastro-esophageal reflux is thought to comprise a subgroup of p...

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Gastro-esophageal Reflux Disease

Gastro-esophageal reflux (GER) is a physiological phenomenon occurring in every individual. Gastro-esophageal reflux Disease (GERD) is a pathological condition where the reflux into the esophagus causes local changes and aspiration of the gastric contents in to the lungs can cause serious, even life threatening conditions. GERD is common but under-diagnosed condition in children. There are fund...

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Distinguishing eosinophilic esophagitis from gastroesophageal reflux disease upon PPI refractoriness: what about PPI-responsive esophageal eosinophilia?

on PPI therapy [3–7] , leading to the description of a new potential disease phenotype in the 2011 updated guidelines, i.e. PPI-responsive esophageal eosinophilia (PPIRee) [8] . Whether these patients represent a sub-phenotype of GERD, EoE or a combined mechanism of both disorders remains unknown. In the aforementioned reports neither histological specific features [6] , pH esophageal monitorin...

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Endoscopic evaluation of gastro-esophageal reflux disease.

Endoscopy is, currently, the initial investigation of choice for the investigation of gastroesophageal reflux disease (GERD) in clinical practice and clinical research. Erosion severity is predictive of a patient's response to therapy and of the likelihood of relapse after therapy. It is, therefore, important to grade the severity of erosive reflux esophagitis, particularly in the context of cl...

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Esophageal motility in eosinophilic esophagitis.

BACKGROUND Eosinophilic esophagitis (EoE) is characterized by eosinophilic infiltration of the esophagus and is a potential cause of dysphagia and food impaction, most commonly affecting young men. Esophageal manometry findings vary from normal motility to aperistalsis, simultaneous contractions, diffuse esophageal spasm, nutcracker esophagus or hypotonic lower esophageal sphincter (LES). It re...

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ژورنال

عنوان ژورنال: Pediatric Reports

سال: 2014

ISSN: 2036-7503,2036-749X

DOI: 10.4081/pr.2014.5160